No, there is no credible evidence that the Disney Junior character Doc McStuffins died of cancer. The theory that she is a cancer patient who imagines her toys coming to life due to medication appears to be an unfounded fan speculation that has spread online.
In the actual show, Doc McStuffins is a young girl who wants to be a doctor like her mother. She practices medicine on her stuffed animals using a magical stethoscope, which brings them to life. The show has tackled the topic of childhood cancer in an episode about a doll whose owner is undergoing chemotherapy, but Doc herself is not portrayed as having cancer.
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The show’s creator Chris Nee has not confirmed or lent any credence to the cancer theory. While fan theories can be creative, in this case the available evidence strongly suggests that the popular children’s series is simply a lighthearted show about a girl’s imaginative play, not a dark story about a terminally ill child. The show ran for 5 seasons from 2012 to 2020 and received a Peabody Award in 2014,